000 01598 a2200433 4500
005 20250515203047.0
264 0 _c20100223
008 201002s 0 0 eng d
022 _a1532-1827
024 7 _a10.1038/sj.bjc.6605507
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTrarbach, T
245 0 0 _aPhase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer.
_h[electronic resource]
260 _bBritish journal of cancer
_cFeb 2010
300 _a506-12 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntibodies, Monoclonal
_xadverse effects
650 0 4 _aAntibodies, Monoclonal, Humanized
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aImmunohistochemistry
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aReceptors, TNF-Related Apoptosis-Inducing Ligand
_xagonists
700 1 _aMoehler, M
700 1 _aHeinemann, V
700 1 _aKöhne, C-H
700 1 _aPrzyborek, M
700 1 _aSchulz, C
700 1 _aSneller, V
700 1 _aGallant, G
700 1 _aKanzler, S
773 0 _tBritish journal of cancer
_gvol. 102
_gno. 3
_gp. 506-12
856 4 0 _uhttps://doi.org/10.1038/sj.bjc.6605507
_zAvailable from publisher's website
999 _c19446823
_d19446823