000 02023 a2200553 4500
005 20250515203038.0
264 0 _c20100412
008 201004s 0 0 eng d
022 _a1557-3265
024 7 _a10.1158/1078-0432.CCR-09-1526
_2doi
040 _aNLM
_beng
_cNLM
100 1 _avan der Bol, Jessica M
245 0 0 _aA CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
_h[electronic resource]
260 _bClinical cancer research : an official journal of the American Association for Cancer Research
_cJan 2010
300 _a736-42 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAlgorithms
650 0 4 _aAntineoplastic Agents, Phytogenic
_xadministration & dosage
650 0 4 _aCamptothecin
_xadministration & dosage
650 0 4 _aCarcinoma
_xdrug therapy
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aCytochrome P-450 CYP3A
_xgenetics
650 0 4 _aDrug Dosage Calculations
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aIndividuality
650 0 4 _aIrinotecan
650 0 4 _aMale
650 0 4 _aMidazolam
_xadministration & dosage
650 0 4 _aMiddle Aged
650 0 4 _aModels, Biological
650 0 4 _aNeoplasm Metastasis
650 0 4 _aPhenotype
650 0 4 _aPrecision Medicine
_xmethods
650 0 4 _aProdrugs
_xadministration & dosage
700 1 _aMathijssen, Ron H J
700 1 _aCreemers, Geert-Jan M
700 1 _aPlanting, André S Th
700 1 _aLoos, Walter J
700 1 _aWiemer, Erik A C
700 1 _aFriberg, Lena E
700 1 _aVerweij, Jaap
700 1 _aSparreboom, Alex
700 1 _ade Jong, Floris A
773 0 _tClinical cancer research : an official journal of the American Association for Cancer Research
_gvol. 16
_gno. 2
_gp. 736-42
856 4 0 _uhttps://doi.org/10.1158/1078-0432.CCR-09-1526
_zAvailable from publisher's website
999 _c19446386
_d19446386