000 02208 a2200637 4500
005 20250515202559.0
264 0 _c20100322
008 201003s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-09-0938
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWalton, Michael I
245 0 0 _aThe preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cJan 2010
300 _a89-100 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xpharmacology
650 0 4 _aBiomarkers, Tumor
_xmetabolism
650 0 4 _aCamptothecin
_xadministration & dosage
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCheckpoint Kinase 1
650 0 4 _aDNA Damage
650 0 4 _aDeoxycytidine
_xadministration & dosage
650 0 4 _aDrug Synergism
650 0 4 _aG2 Phase
_xdrug effects
650 0 4 _aHumans
650 0 4 _aIrinotecan
650 0 4 _aIsoquinolines
_xadministration & dosage
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMutagens
_xtoxicity
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xadministration & dosage
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aPyrazines
_xadministration & dosage
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _aGemcitabine
700 1 _aEve, Paul D
700 1 _aHayes, Angela
700 1 _aValenti, Melanie
700 1 _aDe Haven Brandon, Alexis
700 1 _aBox, Gary
700 1 _aBoxall, Kathy J
700 1 _aAherne, G Wynne
700 1 _aEccles, Suzanne A
700 1 _aRaynaud, Florence I
700 1 _aWilliams, David H
700 1 _aReader, John C
700 1 _aCollins, Ian
700 1 _aGarrett, Michelle D
773 0 _tMolecular cancer therapeutics
_gvol. 9
_gno. 1
_gp. 89-100
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-09-0938
_zAvailable from publisher's website
999 _c19432891
_d19432891