000 01875 a2200529 4500
005 20250515201305.0
264 0 _c20100506
008 201005s 0 0 eng d
022 _a1432-1041
024 7 _a10.1007/s00228-009-0760-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPolasek, Thomas M
245 0 0 _aIn vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.
_h[electronic resource]
260 _bEuropean journal of clinical pharmacology
_cMar 2010
300 _a275-83 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAge Factors
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aArea Under Curve
650 0 4 _aComputer Simulation
650 0 4 _aCytochrome P-450 CYP3A
_xmetabolism
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Interactions
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aLiver
_xdrug effects
650 0 4 _aMale
650 0 4 _aMetabolic Clearance Rate
650 0 4 _aMicrosomes, Liver
_xenzymology
650 0 4 _aMidazolam
_xadministration & dosage
650 0 4 _aModels, Biological
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aRecombinant Proteins
_xantagonists & inhibitors
650 0 4 _aYoung Adult
650 0 4 _aZolpidem
700 1 _aSadagopal, Janani S
700 1 _aElliot, David J
700 1 _aMiners, John O
773 0 _tEuropean journal of clinical pharmacology
_gvol. 66
_gno. 3
_gp. 275-83
856 4 0 _uhttps://doi.org/10.1007/s00228-009-0760-2
_zAvailable from publisher's website
999 _c19393903
_d19393903