| 000 | 01314 a2200349 4500 | ||
|---|---|---|---|
| 005 | 20250515195744.0 | ||
| 264 | 0 | _c20100427 | |
| 008 | 201004s 0 0 eng d | ||
| 022 | _a1464-3391 | ||
| 024 | 7 |
_a10.1016/j.bmc.2009.10.055 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDietrich, Justin | |
| 245 | 0 | 0 |
_aApplication of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry _cJan 2010 |
||
| 300 |
_a292-304 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aCyclization |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImidazoles _xchemical synthesis |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemistry |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins B-raf _xantagonists & inhibitors |
| 700 | 1 | _aGokhale, Vijay | |
| 700 | 1 | _aWang, Xiadong | |
| 700 | 1 | _aHurley, Laurence H | |
| 700 | 1 | _aFlynn, Gary A | |
| 773 | 0 |
_tBioorganic & medicinal chemistry _gvol. 18 _gno. 1 _gp. 292-304 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmc.2009.10.055 _zAvailable from publisher's website |
| 999 |
_c19345149 _d19345149 |
||