000 02304 a2200613 4500
005 20250515195041.0
264 0 _c20100222
008 201002s 0 0 eng d
022 _a1083-351X
024 7 _a10.1074/jbc.M109.055764
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFreschauf, Gary K
245 0 0 _aMechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cJan 2010
300 _a2351-60 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenosine Triphosphate
_xmetabolism
650 0 4 _aAntineoplastic Agents, Phytogenic
_xpharmacology
650 0 4 _aBinding Sites
650 0 4 _aCamptothecin
_xpharmacology
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCircular Dichroism
650 0 4 _aDNA Ligase ATP
650 0 4 _aDNA Ligases
_xantagonists & inhibitors
650 0 4 _aDNA Polymerase beta
_xantagonists & inhibitors
650 0 4 _aDNA Repair
_xdrug effects
650 0 4 _aDNA Repair Enzymes
_xantagonists & inhibitors
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aEtoposide
_xpharmacology
650 0 4 _aFluorescence Resonance Energy Transfer
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aPhosphotransferases (Alcohol Group Acceptor)
_xantagonists & inhibitors
650 0 4 _aPhotoelectron Spectroscopy
650 0 4 _aPiperidines
_xpharmacology
650 0 4 _aPoly-ADP-Ribose Binding Proteins
650 0 4 _aProtein Conformation
650 0 4 _aPyrroles
_xchemistry
650 0 4 _aRadiation-Sensitizing Agents
_xpharmacology
650 0 4 _aTumor Cells, Cultured
650 0 4 _aXenopus Proteins
700 1 _aMani, Rajam S
700 1 _aMereniuk, Todd R
700 1 _aFanta, Mesfin
700 1 _aVirgen, Caesar A
700 1 _aDianov, Grigory L
700 1 _aGrassot, Jean-Marie
700 1 _aHall, Dennis G
700 1 _aWeinfeld, Michael
773 0 _tThe Journal of biological chemistry
_gvol. 285
_gno. 4
_gp. 2351-60
856 4 0 _uhttps://doi.org/10.1074/jbc.M109.055764
_zAvailable from publisher's website
999 _c19324133
_d19324133