000 01859 a2200469 4500
005 20250515193253.0
264 0 _c20091221
008 200912s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm901278z
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSrinivasan, Balasubramanian
245 0 0 _aStructure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 2009
300 _a7228-35 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Transformation, Neoplastic
650 0 4 _aChalcone
_xanalogs & derivatives
650 0 4 _aChalcones
_xchemistry
650 0 4 _aFemale
650 0 4 _aGenes, Reporter
650 0 4 _aHumans
650 0 4 _aI-kappa B Kinase
_xantagonists & inhibitors
650 0 4 _aInhibitory Concentration 50
650 0 4 _aInterleukin-1 Receptor-Associated Kinases
_xantagonists & inhibitors
650 0 4 _aLuciferases
_xmetabolism
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Necrosis Factor-alpha
_xpharmacology
700 1 _aJohnson, Thomas E
700 1 _aLad, Rahul
700 1 _aXing, Chengguo
773 0 _tJournal of medicinal chemistry
_gvol. 52
_gno. 22
_gp. 7228-35
856 4 0 _uhttps://doi.org/10.1021/jm901278z
_zAvailable from publisher's website
999 _c19271626
_d19271626