000 01564 a2200457 4500
005 20250515190748.0
264 0 _c20091116
008 200911s 0 0 eng d
022 _a1546-170X
024 7 _a10.1038/nm.1990
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aOney, Sabah
245 0 0 _aDevelopment of universal antidotes to control aptamer activity.
_h[electronic resource]
260 _bNature medicine
_cOct 2009
300 _a1224-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnticoagulants
_xadverse effects
650 0 4 _aAntidotes
_xadministration & dosage
650 0 4 _aAptamers, Nucleotide
_xclassification
650 0 4 _aDrug Delivery Systems
650 0 4 _aDrug Design
650 0 4 _aFactor IX
_xantagonists & inhibitors
650 0 4 _aFactor Xa Inhibitors
650 0 4 _aHumans
650 0 4 _aNucleic Acid Conformation
_xdrug effects
650 0 4 _aOligonucleotides
_xpharmacology
650 0 4 _aProtamines
_xpharmacology
650 0 4 _aTime Factors
700 1 _aLam, Ruby T S
700 1 _aBompiani, Kristin M
700 1 _aBlake, Charlene M
700 1 _aQuick, George
700 1 _aHeidel, Jeremy D
700 1 _aLiu, Joanna Yi-Ching
700 1 _aMack, Brendan C
700 1 _aDavis, Mark E
700 1 _aLeong, Kam W
700 1 _aSullenger, Bruce A
773 0 _tNature medicine
_gvol. 15
_gno. 10
_gp. 1224-8
856 4 0 _uhttps://doi.org/10.1038/nm.1990
_zAvailable from publisher's website
999 _c19197298
_d19197298