000 02199 a2200577 4500
005 20250515185916.0
264 0 _c20100126
008 201001s 0 0 eng d
022 _a1521-009X
024 7 _a10.1124/dmd.109.029728
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBackman, Janne T
245 0 0 _aCYP2C8 activity recovers within 96 hours after gemfibrozil dosing: estimation of CYP2C8 half-life using repaglinide as an in vivo probe.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cDec 2009
300 _a2359-66 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aArea Under Curve
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xantagonists & inhibitors
650 0 4 _aBiotransformation
650 0 4 _aBlood Glucose
_xdrug effects
650 0 4 _aCarbamates
_xadministration & dosage
650 0 4 _aCross-Over Studies
650 0 4 _aCytochrome P-450 CYP2C8
650 0 4 _aDrug Interactions
650 0 4 _aEnzyme Inhibitors
_xadministration & dosage
650 0 4 _aFemale
650 0 4 _aGemfibrozil
_xadministration & dosage
650 0 4 _aGenotype
650 0 4 _aGlucuronates
_xblood
650 0 4 _aHalf-Life
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xadministration & dosage
650 0 4 _aHypolipidemic Agents
_xadministration & dosage
650 0 4 _aLiver-Specific Organic Anion Transporter 1
650 0 4 _aMale
650 0 4 _aModels, Biological
650 0 4 _aMolecular Probes
_xadministration & dosage
650 0 4 _aOrganic Anion Transporters
_xgenetics
650 0 4 _aPhenotype
650 0 4 _aPiperidines
_xadministration & dosage
650 0 4 _aYoung Adult
700 1 _aHonkalammi, Johanna
700 1 _aNeuvonen, Mikko
700 1 _aKurkinen, Kaisa J
700 1 _aTornio, Aleksi
700 1 _aNiemi, Mikko
700 1 _aNeuvonen, Pertti J
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 37
_gno. 12
_gp. 2359-66
856 4 0 _uhttps://doi.org/10.1124/dmd.109.029728
_zAvailable from publisher's website
999 _c19170517
_d19170517