000 01388 a2200385 4500
005 20250515185449.0
264 0 _c20100414
008 201004s 0 0 eng d
022 _a1432-0614
024 7 _a10.1007/s00253-009-2232-0
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWu, Dan
245 0 0 _aIncomplete formation of intramolecular disulfide bond triggers degradation and aggregation of human consensus interferon-alpha mutant by Pichia pastoris.
_h[electronic resource]
260 _bApplied microbiology and biotechnology
_cFeb 2010
300 _a1759-67 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aBioreactors
650 0 4 _aDisulfides
_xmetabolism
650 0 4 _aElectrophoresis, Gel, Two-Dimensional
650 0 4 _aFermentation
650 0 4 _aHumans
650 0 4 _aInterferon-alpha
_xbiosynthesis
650 0 4 _aMutation
650 0 4 _aPichia
_xgenetics
650 0 4 _aProtein Stability
650 0 4 _aRecombinant Proteins
_xbiosynthesis
700 1 _aMa, Dong
700 1 _aHao, Yu-You
700 1 _aChu, Ju
700 1 _aWang, Yong-Hong
700 1 _aZhuang, Ying-Ping
700 1 _aZhang, Si-Liang
773 0 _tApplied microbiology and biotechnology
_gvol. 85
_gno. 6
_gp. 1759-67
856 4 0 _uhttps://doi.org/10.1007/s00253-009-2232-0
_zAvailable from publisher's website
999 _c19157681
_d19157681