| 000 | 01860 a2200493 4500 | ||
|---|---|---|---|
| 005 | 20250515183529.0 | ||
| 264 | 0 | _c20110228 | |
| 008 | 201102s 0 0 eng d | ||
| 022 | _a1573-501X | ||
| 024 | 7 |
_a10.1007/s11030-009-9172-6 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKumar, Manoj | |
| 245 | 0 | 0 |
_aIn silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery. _h[electronic resource] |
| 260 |
_bMolecular diversity _cAug 2010 |
||
| 300 |
_a595-604 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 |
_aAntitubercular Agents _xchemistry |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 |
_aComputational Biology _xmethods |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aFolic Acid Antagonists _xchemistry |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHydrogen Bonding _xdrug effects |
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 |
_aMethotrexate _xchemistry |
| 650 | 0 | 4 | _aMicrobial Sensitivity Tests |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 | _aMolecular Sequence Data |
| 650 | 0 | 4 |
_aMycobacterium tuberculosis _xdrug effects |
| 650 | 0 | 4 |
_aOrnithine _xanalogs & derivatives |
| 650 | 0 | 4 |
_aPeptides _xchemistry |
| 650 | 0 | 4 |
_aPterins _xchemistry |
| 650 | 0 | 4 | _aReproducibility of Results |
| 650 | 0 | 4 |
_aSubstrate Specificity _xdrug effects |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xmetabolism |
| 650 | 0 | 4 |
_aTriazines _xchemistry |
| 650 | 0 | 4 |
_aTuberculosis _xdrug therapy |
| 700 | 1 | _aVijayakrishnan, Rajakrishnan | |
| 700 | 1 | _aSubba Rao, Gita | |
| 773 | 0 |
_tMolecular diversity _gvol. 14 _gno. 3 _gp. 595-604 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1007/s11030-009-9172-6 _zAvailable from publisher's website |
| 999 |
_c19099405 _d19099405 |
||