000 02536 a2200721 4500
005 20250515183525.0
264 0 _c20091203
008 200912s 0 0 eng d
022 _a1553-7374
024 7 _a10.1371/journal.ppat.1000559
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aShio, Marina Tiemi
245 0 0 _aMalarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
_h[electronic resource]
260 _bPLoS pathogens
_cAug 2009
300 _ae1000559 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis Regulatory Proteins
_ximmunology
650 0 4 _aCARD Signaling Adaptor Proteins
650 0 4 _aCalcium-Binding Proteins
_ximmunology
650 0 4 _aCarrier Proteins
_ximmunology
650 0 4 _aCaspase 1
_ximmunology
650 0 4 _aCathepsin B
_xmetabolism
650 0 4 _aCytoskeletal Proteins
_ximmunology
650 0 4 _aDisease Models, Animal
650 0 4 _aFemale
650 0 4 _aHSP90 Heat-Shock Proteins
_xmetabolism
650 0 4 _aHemeproteins
_ximmunology
650 0 4 _aHumans
650 0 4 _aInflammation
_ximmunology
650 0 4 _aInterleukin-1beta
_xbiosynthesis
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xmetabolism
650 0 4 _aMalaria
_ximmunology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aNLR Family, Pyrin Domain-Containing 3 Protein
650 0 4 _aNeutrophil Infiltration
_ximmunology
650 0 4 _aPhagocytosis
650 0 4 _aPhosphorylation
_ximmunology
650 0 4 _aPlasmodium chabaudi
_xchemistry
650 0 4 _aPotassium
_xmetabolism
650 0 4 _aProtein-Tyrosine Kinases
_xmetabolism
650 0 4 _aProteomics
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aSignal Transduction
_ximmunology
650 0 4 _aSyk Kinase
650 0 4 _asrc-Family Kinases
_xmetabolism
700 1 _aTiemi Shio, Marina
700 1 _aEisenbarth, Stephanie C
700 1 _aSavaria, Myriam
700 1 _aVinet, Adrien F
700 1 _aBellemare, Marie-Josée
700 1 _aHarder, Kenneth W
700 1 _aSutterwala, Fayyaz S
700 1 _aBohle, D Scott
700 1 _aDescoteaux, Albert
700 1 _aFlavell, Richard A
700 1 _aOlivier, Martin
773 0 _tPLoS pathogens
_gvol. 5
_gno. 8
_gp. e1000559
856 4 0 _uhttps://doi.org/10.1371/journal.ppat.1000559
_zAvailable from publisher's website
999 _c19099158
_d19099158