000 02433 a2200613 4500
005 20250515181925.0
264 0 _c20100813
008 201008s 0 0 eng d
022 _a1557-8534
024 7 _a10.1089/scd.2009.0147
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLee, Kyu-Won
245 0 0 _aRapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
_h[electronic resource]
260 _bStem cells and development
_cApr 2010
300 _a557-68 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aBiomarkers
650 0 4 _aBone Morphogenetic Protein Receptors
_xgenetics
650 0 4 _aCell Differentiation
_xdrug effects
650 0 4 _aCell Line
650 0 4 _aChromones
_xpharmacology
650 0 4 _aCore Binding Factor Alpha 1 Subunit
_xgenetics
650 0 4 _aEmbryonic Stem Cells
_xcytology
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHomeodomain Proteins
_xgenetics
650 0 4 _aHumans
650 0 4 _aImmunosuppressive Agents
_xpharmacology
650 0 4 _aInhibitor of Differentiation Protein 1
_xgenetics
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xantagonists & inhibitors
650 0 4 _aMorpholines
_xpharmacology
650 0 4 _aNanog Homeobox Protein
650 0 4 _aOctamer Transcription Factor-3
_xgenetics
650 0 4 _aOsteoblasts
_xcytology
650 0 4 _aOsteogenesis
_xdrug effects
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-akt
_xantagonists & inhibitors
650 0 4 _aRNA, Messenger
650 0 4 _aRibosomal Protein S6 Kinases, 70-kDa
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSirolimus
_xpharmacology
650 0 4 _aSmad Proteins
_xmetabolism
650 0 4 _aTOR Serine-Threonine Kinases
650 0 4 _aTacrolimus
_xpharmacology
700 1 _aYook, Jin-Yong
700 1 _aSon, Mi-Young
700 1 _aKim, Min-Jeong
700 1 _aKoo, Deog-Bon
700 1 _aHan, Yong-Mahn
700 1 _aCho, Yee Sook
773 0 _tStem cells and development
_gvol. 19
_gno. 4
_gp. 557-68
856 4 0 _uhttps://doi.org/10.1089/scd.2009.0147
_zAvailable from publisher's website
999 _c19050439
_d19050439