000 01660 a2200481 4500
005 20250515175824.0
264 0 _c20091013
008 200910s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2009.05.082
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYe, Yang-liang
245 0 0 _aDiscovery of novel dual functional agent as PPARgamma agonist and 11beta-HSD1 inhibitor for the treatment of diabetes.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cAug 2009
300 _a5722-32 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a11-beta-Hydroxysteroid Dehydrogenase Type 1
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aBody Weight
_xdrug effects
650 0 4 _aDiabetes Mellitus, Experimental
_xdrug therapy
650 0 4 _aFats
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xchemistry
650 0 4 _aHypolipidemic Agents
_xchemistry
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aObesity
_xchemically induced
650 0 4 _aPPAR gamma
_xagonists
650 0 4 _aPhenylpropionates
_xchemistry
650 0 4 _aRats
650 0 4 _aRats, Wistar
700 1 _aZhou, Zhou
700 1 _aZou, Han-jun
700 1 _aShen, Yu
700 1 _aXu, Ti-Fei
700 1 _aTang, Jing
700 1 _aYin, Hua-zhong
700 1 _aChen, Min-li
700 1 _aLeng, Ying
700 1 _aShen, Jian-hua
773 0 _tBioorganic & medicinal chemistry
_gvol. 17
_gno. 15
_gp. 5722-32
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2009.05.082
_zAvailable from publisher's website
999 _c18990161
_d18990161