000 02020 a2200505 4500
005 20250515175510.0
264 0 _c20090909
008 200909s 0 0 eng d
022 _a1091-6490
024 7 _a10.1073/pnas.0905930106
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLu, Jie
245 0 0 _aInhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cJul 2009
300 _a11697-702 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents, Alkylating
_xtherapeutic use
650 0 4 _aBlotting, Western
650 0 4 _aCell Cycle Proteins
_xmetabolism
650 0 4 _aDNA Damage
650 0 4 _aDacarbazine
_xanalogs & derivatives
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFlow Cytometry
650 0 4 _aFluorescent Antibody Technique
650 0 4 _aGene Expression Regulation, Enzymologic
_xdrug effects
650 0 4 _aGlioblastoma
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, SCID
650 0 4 _aNeuroblastoma
_xdrug therapy
650 0 4 _aProtein Phosphatase 2
_xantagonists & inhibitors
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aTemozolomide
650 0 4 _aPolo-Like Kinase 1
700 1 _aKovach, John S
700 1 _aJohnson, Francis
700 1 _aChiang, Jeffrey
700 1 _aHodes, Richard
700 1 _aLonser, Russell
700 1 _aZhuang, Zhengping
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 106
_gno. 28
_gp. 11697-702
856 4 0 _uhttps://doi.org/10.1073/pnas.0905930106
_zAvailable from publisher's website
999 _c18981542
_d18981542