000 01968 a2200529 4500
005 20250515175203.0
264 0 _c20101021
008 201010s 0 0 eng d
022 _a1573-0646
024 7 _a10.1007/s10637-009-9281-1
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBrĂ¼ning, Ansgar
245 0 0 _aNelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib.
_h[electronic resource]
260 _bInvestigational new drugs
_cOct 2010
300 _a535-42 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnnexin A5
_xmetabolism
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzenesulfonates
_xpharmacology
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aDrug Synergism
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xmetabolism
650 0 4 _aFemale
650 0 4 _aHIV Protease Inhibitors
_xpharmacology
650 0 4 _aHumans
650 0 4 _aMembrane Potential, Mitochondrial
_xdrug effects
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aMyeloid Cell Leukemia Sequence 1 Protein
650 0 4 _aNelfinavir
_xpharmacology
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aOvarian Neoplasms
_xenzymology
650 0 4 _aPhenylurea Compounds
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPropidium
_xmetabolism
650 0 4 _aProtein Stability
_xdrug effects
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xmetabolism
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aSorafenib
700 1 _aBurger, Petra
700 1 _aVogel, Marianne
700 1 _aGingelmaier, Andrea
700 1 _aFriese, Klaus
700 1 _aBurges, Alexander
773 0 _tInvestigational new drugs
_gvol. 28
_gno. 5
_gp. 535-42
856 4 0 _uhttps://doi.org/10.1007/s10637-009-9281-1
_zAvailable from publisher's website
999 _c18971760
_d18971760