000 02034 a2200589 4500
005 20250515173223.0
264 0 _c20100426
008 201004s 0 0 eng d
022 _a1540-8167
024 7 _a10.1111/j.1540-8167.2009.01468.x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhao, Jing Ting
245 0 0 _aNot all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype.
_h[electronic resource]
260 _bJournal of cardiovascular electrophysiology
_cAug 2009
300 _a923-30 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aCHO Cells
650 0 4 _aCell Line
650 0 4 _aChild
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aERG1 Potassium Channel
650 0 4 _aEther-A-Go-Go Potassium Channels
_xantagonists & inhibitors
650 0 4 _aFemale
650 0 4 _aGene Silencing
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutation
_xgenetics
650 0 4 _aPedigree
650 0 4 _aPhenotype
650 0 4 _aProtein Structure, Tertiary
_xgenetics
650 0 4 _aProtein Transport
_xgenetics
650 0 4 _aSeverity of Illness Index
650 0 4 _aYoung Adult
700 1 _aHill, Adam P
700 1 _aVarghese, Anthony
700 1 _aCooper, Antony A
700 1 _aSwan, Heikki
700 1 _aLaitinen-Forsblom, Päivi J
700 1 _aRees, Mark I
700 1 _aSkinner, Jonathan R
700 1 _aCampbell, Terence J
700 1 _aVandenberg, Jamie I
773 0 _tJournal of cardiovascular electrophysiology
_gvol. 20
_gno. 8
_gp. 923-30
856 4 0 _uhttps://doi.org/10.1111/j.1540-8167.2009.01468.x
_zAvailable from publisher's website
999 _c18914908
_d18914908