| 000 | 01558 a2200397 4500 | ||
|---|---|---|---|
| 005 | 20250515172950.0 | ||
| 264 | 0 | _c20090903 | |
| 008 | 200909s 0 0 eng d | ||
| 022 | _a1872-7786 | ||
| 024 | 7 |
_a10.1016/j.cbi.2009.05.014 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWen, Bo | |
| 245 | 0 | 0 |
_aMetabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s. _h[electronic resource] |
| 260 |
_bChemico-biological interactions _cOct 2009 |
||
| 300 |
_a220-6 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAntipsychotic Agents _xpharmacokinetics |
| 650 | 0 | 4 | _aBiotransformation |
| 650 | 0 | 4 |
_aChlorpromazine _xpharmacokinetics |
| 650 | 0 | 4 | _aChromatography, High Pressure Liquid |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2D6 _xmetabolism |
| 650 | 0 | 4 | _aCytochrome P-450 CYP2D6 Inhibitors |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
| 650 | 0 | 4 |
_aGlutathione _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aIn Vitro Techniques |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xenzymology |
| 650 | 0 | 4 |
_aQuinidine _xpharmacology |
| 650 | 0 | 4 |
_aQuinones _xpharmacokinetics |
| 650 | 0 | 4 | _aTandem Mass Spectrometry |
| 650 | 0 | 4 |
_aThioridazine _xpharmacokinetics |
| 700 | 1 | _aZhou, Mingyan | |
| 773 | 0 |
_tChemico-biological interactions _gvol. 181 _gno. 2 _gp. 220-6 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.cbi.2009.05.014 _zAvailable from publisher's website |
| 999 |
_c18907020 _d18907020 |
||