000			02338 a2200613 4500
005			20250515165428.0
264		0	_c20090608
008			200906s 0 0 eng d
022			_a1535-7163
024	7		_a10.1158/1535-7163.MCT-08-1080 _2doi
040			_aNLM _beng _cNLM
100	1		_aDeng, Rong
245	0	0	_aExcisaninA, a diterpenoid compound purified from Isodon MacrocalyxinD, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of its signal pathway. _h[electronic resource]
260			_bMolecular cancer therapeutics _cApr 2009
300			_a873-82 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_a3-Phosphoinositide-Dependent Protein Kinases
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aBlotting, Western
650	0	4	_aBreast Neoplasms _xdrug therapy
650	0	4	_aCarcinoma, Hepatocellular _xdrug therapy
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDiterpenes _xpharmacology
650	0	4	_aDrugs, Chinese Herbal _xpharmacology
650	0	4	_aFluorescent Antibody Technique
650	0	4	_aHumans
650	0	4	_aIn Situ Nick-End Labeling
650	0	4	_aIsodon _xchemistry
650	0	4	_aLiver Neoplasms _xdrug therapy
650	0	4	_aMice
650	0	4	_aMice, Inbred BALB C
650	0	4	_aMice, Nude
650	0	4	_aProtein Serine-Threonine Kinases _xantagonists & inhibitors
650	0	4	_aProto-Oncogene Proteins c-akt _xantagonists & inhibitors
650	0	4	_aRNA, Messenger _xgenetics
650	0	4	_aRNA, Small Interfering _xpharmacology
650	0	4	_aReverse Transcriptase Polymerase Chain Reaction
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aTumor Cells, Cultured
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aTang, Jun
700	1		_aXia, Liang-Ping
700	1		_aLi, Dan-Dan
700	1		_aZhou, Wen-Jun
700	1		_aWang, Lin-Lin
700	1		_aFeng, Gong-Kan
700	1		_aZeng, Yi-Xin
700	1		_aGao, You-Heng
700	1		_aZhu, Xiao-Feng
773	0		_tMolecular cancer therapeutics _gvol. 8 _gno. 4 _gp. 873-82
856	4	0	_uhttps://doi.org/10.1158/1535-7163.MCT-08-1080 _zAvailable from publisher's website
999			_c18804339 _d18804339