| 000 | 01621 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250515165422.0 | ||
| 264 | 0 | _c20090928 | |
| 008 | 200909s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.108.026245 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aYuan, Haodan | |
| 245 | 0 | 0 |
_aEvaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cJul 2009 |
||
| 300 |
_a1443-7 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAlkaline Phosphatase _xmetabolism |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aCaco-2 Cells _xenzymology |
| 650 | 0 | 4 | _aDrug Delivery Systems |
| 650 | 0 | 4 | _aDrug Stability |
| 650 | 0 | 4 |
_aFluconazole _xadministration & dosage |
| 650 | 0 | 4 | _aHalf-Life |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydrogen-Ion Concentration |
| 650 | 0 | 4 | _aIntestinal Absorption |
| 650 | 0 | 4 |
_aIntestines _xcytology |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMucous Membrane _xdrug effects |
| 650 | 0 | 4 |
_aOrganophosphates _xadministration & dosage |
| 650 | 0 | 4 |
_aPhenytoin _xanalogs & derivatives |
| 650 | 0 | 4 |
_aPhosphates _xmetabolism |
| 650 | 0 | 4 |
_aProdrugs _xpharmacology |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aSolubility |
| 700 | 1 | _aLi, Na | |
| 700 | 1 | _aLai, Yurong | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 37 _gno. 7 _gp. 1443-7 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.108.026245 _zAvailable from publisher's website |
| 999 |
_c18804015 _d18804015 |
||