| 000 | 01955 a2200637 4500 | ||
|---|---|---|---|
| 005 | 20250515164929.0 | ||
| 264 | 0 | _c20090602 | |
| 008 | 200906s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm8016514 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aJiang, Jinlong | |
| 245 | 0 | 0 |
_aPotent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cMay 2009 |
||
| 300 |
_a3039-46 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAprepitant |
| 650 | 0 | 4 |
_aBrain _xmetabolism |
| 650 | 0 | 4 | _aCHO Cells |
| 650 | 0 | 4 | _aCricetinae |
| 650 | 0 | 4 | _aCricetulus |
| 650 | 0 | 4 | _aDrug Interactions |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aInhibitory Concentration 50 |
| 650 | 0 | 4 |
_aIsoindoles _xchemical synthesis |
| 650 | 0 | 4 | _aMacaca mulatta |
| 650 | 0 | 4 |
_aMorpholines _xpharmacology |
| 650 | 0 | 4 | _aNeurokinin-1 Receptor Antagonists |
| 650 | 0 | 4 | _aStereoisomerism |
| 700 | 1 | _aBunda, Jaime L | |
| 700 | 1 | _aDoss, Geoge A | |
| 700 | 1 | _aChicchi, Gary G | |
| 700 | 1 | _aKurtz, Marc M | |
| 700 | 1 | _aTsao, Kwei-Lan C | |
| 700 | 1 | _aTong, Xinchun | |
| 700 | 1 | _aZheng, Song | |
| 700 | 1 | _aUpthagrove, Alana | |
| 700 | 1 | _aSamuel, Koppara | |
| 700 | 1 | _aTschirret-Guth, Richard | |
| 700 | 1 | _aKumar, Sanjeev | |
| 700 | 1 | _aWheeldon, Alan | |
| 700 | 1 | _aCarlson, Emma J | |
| 700 | 1 | _aHargreaves, Richard | |
| 700 | 1 | _aBurns, Donald | |
| 700 | 1 | _aHamill, Terence | |
| 700 | 1 | _aRyan, Christine | |
| 700 | 1 | _aKrause, Stephen M | |
| 700 | 1 | _aEng, WaiSi | |
| 700 | 1 | _aDeVita, Robert J | |
| 700 | 1 | _aMills, Sander G | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 52 _gno. 9 _gp. 3039-46 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm8016514 _zAvailable from publisher's website |
| 999 |
_c18788414 _d18788414 |
||