000 01864 a2200553 4500
005 20250515164131.0
264 0 _c20090821
008 200908s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2009.03.005
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDebenham, John S
245 0 0 _aPyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cMay 2009
300 _a2591-4 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aCannabinoid Receptor Agonists
650 0 4 _aCannabinoids
_xchemistry
650 0 4 _aChemistry, Pharmaceutical
_xmethods
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aObesity
_xdrug therapy
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aPyrimidines
_xchemistry
650 0 4 _aRats
650 0 4 _aReceptor, Cannabinoid, CB1
_xagonists
650 0 4 _aReceptor, Cannabinoid, CB2
_xagonists
650 0 4 _aStructure-Activity Relationship
700 1 _aMadsen-Duggan, Christina B
700 1 _aWang, Junying
700 1 _aTong, Xinchun
700 1 _aLao, Julie
700 1 _aFong, Tung M
700 1 _aSchaeffer, Marie-Therese
700 1 _aXiao, Jing Chen
700 1 _aHuang, Cathy C R-R
700 1 _aShen, Chun-Pyn
700 1 _aSloan Stribling, D
700 1 _aShearman, Lauren P
700 1 _aStrack, Alison M
700 1 _aEuan Macintyre, D
700 1 _aHale, Jeffrey J
700 1 _aWalsh, Thomas F
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 19
_gno. 9
_gp. 2591-4
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2009.03.005
_zAvailable from publisher's website
999 _c18765300
_d18765300