000			02227 a2200697 4500
005			20250515163902.0
264		0	_c20090506
008			200905s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm900063x _2doi
040			_aNLM _beng _cNLM
100	1		_aVachal, Petr
245	0	0	_a1-Sulfonyl-4-acylpiperazines as selective cannabinoid-1 receptor (CB1R) inverse agonists for the treatment of obesity. _h[electronic resource]
260			_bJournal of medicinal chemistry _cApr 2009
300			_a2550-8 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAnti-Obesity Agents _xchemical synthesis
650	0	4	_aBiological Availability
650	0	4	_aBody Weight _xdrug effects
650	0	4	_aDogs
650	0	4	_aDrug Inverse Agonism
650	0	4	_aEating _xdrug effects
650	0	4	_aHepatocytes _xmetabolism
650	0	4	_aHumans
650	0	4	_aIn Vitro Techniques
650	0	4	_aMacaca mulatta
650	0	4	_aMicrosomes, Liver _xmetabolism
650	0	4	_aModels, Molecular
650	0	4	_aPiperazines _xchemical synthesis
650	0	4	_aRats
650	0	4	_aReceptor, Cannabinoid, CB1 _xantagonists & inhibitors
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
650	0	4	_aSulfonamides _xchemical synthesis
700	1		_aFletcher, Joan M
700	1		_aFong, Tung M
700	1		_aHuang, Cathy C R-R
700	1		_aLao, Julie
700	1		_aXiao, Jing C
700	1		_aShen, Chun-Pyn
700	1		_aStrack, Alison M
700	1		_aShearman, Lauren
700	1		_aStribling, Sloan
700	1		_aChen, Richard Z
700	1		_aFrassetto, Andrea
700	1		_aTong, Xinchun
700	1		_aWang, Junying
700	1		_aBall, Richard G
700	1		_aTsou, Nancy N
700	1		_aHickey, Gerard J
700	1		_aThompson, Donald F
700	1		_aFaidley, Terry D
700	1		_aNicolich, Susan
700	1		_aAchanfuo-Yeboah, Joana
700	1		_aHora, Donald F
700	1		_aHale, Jeffrey J
700	1		_aHagmann, William K
773	0		_tJournal of medicinal chemistry _gvol. 52 _gno. 8 _gp. 2550-8
856	4	0	_uhttps://doi.org/10.1021/jm900063x _zAvailable from publisher's website
999			_c18757571 _d18757571