000 02120 a2200577 4500
005 20250515163526.0
264 0 _c20090602
008 200906s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm801640k
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNudelman, Igor
245 0 0 _aDevelopment of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMay 2009
300 _a2836-45 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAminoglycosides
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aBacteria
_xdrug effects
650 0 4 _aCOS Cells
650 0 4 _aCadherin Related Proteins
650 0 4 _aCadherins
_xgenetics
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aChlorocebus aethiops
650 0 4 _aCodon, Nonsense
_xdrug effects
650 0 4 _aCystic Fibrosis Transmembrane Conductance Regulator
_xgenetics
650 0 4 _aCytoplasm
_xdrug effects
650 0 4 _aDisease
_xgenetics
650 0 4 _aDrug Discovery
650 0 4 _aDystrophin
_xgenetics
650 0 4 _aGentamicins
_xpharmacology
650 0 4 _aHearing Loss
_xchemically induced
650 0 4 _aHumans
650 0 4 _aOligoribonucleotides
_xchemistry
650 0 4 _aParomomycin
_xpharmacology
650 0 4 _aProtein Biosynthesis
_xdrug effects
650 0 4 _aRNA Stability
_xdrug effects
650 0 4 _aRNA, Ribosomal
_xchemistry
650 0 4 _aTemperature
700 1 _aRebibo-Sabbah, Annie
700 1 _aCherniavsky, Marina
700 1 _aBelakhov, Valery
700 1 _aHainrichson, Mariana
700 1 _aChen, Fuquan
700 1 _aSchacht, Jochen
700 1 _aPilch, Daniel S
700 1 _aBen-Yosef, Tamar
700 1 _aBaasov, Timor
773 0 _tJournal of medicinal chemistry
_gvol. 52
_gno. 9
_gp. 2836-45
856 4 0 _uhttps://doi.org/10.1021/jm801640k
_zAvailable from publisher's website
999 _c18746655
_d18746655