000 01932 a2200529 4500
005 20250515162627.0
264 0 _c20090723
008 200907s 0 0 eng d
022 _a1550-7416
024 7 _a10.1208/s12248-009-9090-7
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLester, Henry A
245 0 0 _aNicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.
_h[electronic resource]
260 _bThe AAPS journal
_cMar 2009
300 _a167-77 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
650 0 4 _aAcetylcholine
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aDrug Discovery
650 0 4 _aEndoplasmic Reticulum
_xdrug effects
650 0 4 _aEpilepsy, Frontal Lobe
_xgenetics
650 0 4 _aHippocampus
_xdrug effects
650 0 4 _aMice
650 0 4 _aModels, Biological
650 0 4 _aMuscle Proteins
_xbiosynthesis
650 0 4 _aMutation, Missense
650 0 4 _aNerve Tissue Proteins
_xbiosynthesis
650 0 4 _aNeurotransmitter Agents
_xphysiology
650 0 4 _aNicotine
_xpharmacokinetics
650 0 4 _aParkinson Disease
_xprevention & control
650 0 4 _aReceptors, Nicotinic
_xbiosynthesis
650 0 4 _aSmoking
_xmetabolism
650 0 4 _aTobacco Use Disorder
_xgenetics
650 0 4 _aUp-Regulation
_xdrug effects
650 0 4 _aVentral Tegmental Area
_xdrug effects
700 1 _aXiao, Cheng
700 1 _aSrinivasan, Rahul
700 1 _aSon, Cagdas D
700 1 _aMiwa, Julie
700 1 _aPantoja, Rigo
700 1 _aBanghart, Matthew R
700 1 _aDougherty, Dennis A
700 1 _aGoate, Alison M
700 1 _aWang, Jen C
773 0 _tThe AAPS journal
_gvol. 11
_gno. 1
_gp. 167-77
856 4 0 _uhttps://doi.org/10.1208/s12248-009-9090-7
_zAvailable from publisher's website
999 _c18719834
_d18719834