000 01550 a2200433 4500
005 20250515161918.0
264 0 _c20090624
008 200906s 0 0 eng d
022 _a1366-5928
024 7 _a10.1080/00498250802638155
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPerloff, E S
245 0 0 _aValidation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.
_h[electronic resource]
260 _bXenobiotica; the fate of foreign compounds in biological systems
_cFeb 2009
300 _a99-112 p.
_bdigital
500 _aPublication Type: Journal Article; Validation Study
650 0 4 _aChromatography, Liquid
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aDrug Evaluation, Preclinical
_xmethods
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aTandem Mass Spectrometry
650 0 4 _aTime Factors
700 1 _aMason, A K
700 1 _aDehal, S S
700 1 _aBlanchard, A P
700 1 _aMorgan, L
700 1 _aHo, T
700 1 _aDandeneau, A
700 1 _aCrocker, R M
700 1 _aChandler, C M
700 1 _aBoily, N
700 1 _aCrespi, C L
700 1 _aStresser, D M
773 0 _tXenobiotica; the fate of foreign compounds in biological systems
_gvol. 39
_gno. 2
_gp. 99-112
856 4 0 _uhttps://doi.org/10.1080/00498250802638155
_zAvailable from publisher's website
999 _c18696934
_d18696934