| 000 | 01459 a2200385 4500 | ||
|---|---|---|---|
| 005 | 20250515154923.0 | ||
| 264 | 0 | _c20090219 | |
| 008 | 200902s 0 0 eng d | ||
| 022 | _a1545-7885 | ||
| 024 | 7 |
_a10.1371/journal.pbio.1000017 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aCalleja, Véronique | |
| 245 | 0 | 0 |
_aRole of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. _h[electronic resource] |
| 260 |
_bPLoS biology _cJan 2009 |
||
| 300 |
_ae17 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _a3-Phosphoinositide-Dependent Protein Kinases |
| 650 | 0 | 4 |
_aAllosteric Regulation _xphysiology |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBinding Sites _xdrug effects |
| 650 | 0 | 4 | _aGene Expression Regulation |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMutagenesis |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 |
_aProtein Conformation _xdrug effects |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacology |
| 650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xmetabolism |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-akt _xantagonists & inhibitors |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aLaguerre, Michel | |
| 700 | 1 | _aParker, Peter J | |
| 700 | 1 | _aLarijani, Banafshé | |
| 773 | 0 |
_tPLoS biology _gvol. 7 _gno. 1 _gp. e17 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1371/journal.pbio.1000017 _zAvailable from publisher's website |
| 999 |
_c18612852 _d18612852 |
||