| 000 | 01904 a2200553 4500 | ||
|---|---|---|---|
| 005 | 20250511210241.0 | ||
| 264 | 0 | _c19910312 | |
| 008 | 199103s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm00105a017 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKingsbury, W D | |
| 245 | 0 | 0 |
_aSynthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cJan 1991 |
||
| 300 |
_a98-107 p. _bdigital |
||
| 500 | _aPublication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 |
_aCamptothecin _xanalogs & derivatives |
| 650 | 0 | 4 | _aCattle |
| 650 | 0 | 4 | _aCell Line |
| 650 | 0 | 4 |
_aColonic Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aDNA, Superhelical _xdrug effects |
| 650 | 0 | 4 | _aDrug Evaluation, Preclinical |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aIndicators and Reagents |
| 650 | 0 | 4 |
_aLeukemia L1210 _xdrug therapy |
| 650 | 0 | 4 |
_aLung Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aMelanoma, Experimental _xdrug therapy |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 | _aPlasmids |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aThymus Gland _xenzymology |
| 650 | 0 | 4 | _aTopoisomerase I Inhibitors |
| 650 | 0 | 4 | _aTransplantation, Heterologous |
| 700 | 1 | _aBoehm, J C | |
| 700 | 1 | _aJakas, D R | |
| 700 | 1 | _aHolden, K G | |
| 700 | 1 | _aHecht, S M | |
| 700 | 1 | _aGallagher, G | |
| 700 | 1 | _aCaranfa, M J | |
| 700 | 1 | _aMcCabe, F L | |
| 700 | 1 | _aFaucette, L F | |
| 700 | 1 | _aJohnson, R K | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 34 _gno. 1 _gp. 98-107 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm00105a017 _zAvailable from publisher's website |
| 999 |
_c1853129 _d1853129 |
||