000 02087 a2200529 4500
005 20250515152049.0
264 0 _c20090303
008 200903s 0 0 eng d
022 _a1744-6872
024 7 _a10.1097/FPC.0b013e32831665ea
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLim, Yun-Ping
245 0 0 _aInhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
_h[electronic resource]
260 _bPharmacogenetics and genomics
_cJan 2009
300 _a11-24 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntifungal Agents
_xpharmacology
650 0 4 _aBase Sequence
650 0 4 _aCell Line
650 0 4 _aCytochrome P-450 CYP3A
_xgenetics
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
650 0 4 _aDNA Primers
_xgenetics
650 0 4 _aGene Expression Regulation, Enzymologic
_xdrug effects
650 0 4 _aHeLa Cells
650 0 4 _aHepatocyte Nuclear Factor 4
_xantagonists & inhibitors
650 0 4 _aHistone Acetyltransferases
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aKetoconazole
_xpharmacology
650 0 4 _aLigands
650 0 4 _aNuclear Receptor Coactivator 1
650 0 4 _aPharmacogenetics
650 0 4 _aPregnane X Receptor
650 0 4 _aPromoter Regions, Genetic
650 0 4 _aProtein Interaction Domains and Motifs
650 0 4 _aRNA Interference
650 0 4 _aReceptors, Steroid
_xantagonists & inhibitors
650 0 4 _aRecombinant Proteins
_xantagonists & inhibitors
650 0 4 _aRifampin
_xpharmacology
650 0 4 _aTranscription Factors
_xantagonists & inhibitors
650 0 4 _aTwo-Hybrid System Techniques
700 1 _aKuo, Sheng-Chun
700 1 _aLai, Ming-Liang
700 1 _aHuang, Jin-Ding
773 0 _tPharmacogenetics and genomics
_gvol. 19
_gno. 1
_gp. 11-24
856 4 0 _uhttps://doi.org/10.1097/FPC.0b013e32831665ea
_zAvailable from publisher's website
999 _c18530237
_d18530237