000			02279 a2200637 4500
005			20250515151919.0
264		0	_c20090401
008			200904s 0 0 eng d
022			_a1527-3350
024	7		_a10.1002/hep.22717 _2doi
040			_aNLM _beng _cNLM
100	1		_aKneteman, Norman M
245	0	0	_aHCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus. _h[electronic resource]
260			_bHepatology (Baltimore, Md.) _cMar 2009
300			_a745-52 p. _bdigital
500			_aPublication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAntiviral Agents _xpharmacology
650	0	4	_aBenzofurans _xpharmacology
650	0	4	_aDisease Models, Animal
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDouble-Blind Method
650	0	4	_aDrug Therapy, Combination
650	0	4	_aEnzyme Inhibitors _xpharmacology
650	0	4	_aHepacivirus _xdrug effects
650	0	4	_aHepatitis C _xdrug therapy
650	0	4	_aHepatocytes _xtransplantation
650	0	4	_aHumans
650	0	4	_aInterferon alpha-2
650	0	4	_aInterferon-alpha _xtherapeutic use
650	0	4	_aLiver _xdrug effects
650	0	4	_aMice
650	0	4	_aMice, SCID
650	0	4	_aPolyethylene Glycols
650	0	4	_aRecombinant Proteins
650	0	4	_aReplicon _xdrug effects
650	0	4	_aRibavirin _xtherapeutic use
650	0	4	_aSulfonamides _xpharmacology
650	0	4	_aViral Nonstructural Proteins _xantagonists & inhibitors
700	1		_aHowe, Anita Y M
700	1		_aGao, Tiejun
700	1		_aLewis, Jamie
700	1		_aPevear, Dan
700	1		_aLund, Gary
700	1		_aDouglas, Donna
700	1		_aMercer, David F
700	1		_aTyrrell, D Lorne J
700	1		_aImmermann, Frederick
700	1		_aChaudhary, Inder
700	1		_aSpeth, John
700	1		_aVillano, Stephen A
700	1		_aO'Connell, John
700	1		_aCollett, Marc
773	0		_tHepatology (Baltimore, Md.) _gvol. 49 _gno. 3 _gp. 745-52
856	4	0	_uhttps://doi.org/10.1002/hep.22717 _zAvailable from publisher's website
999			_c18525650 _d18525650