000			02350 a2200709 4500
005			20250515144154.0
264		0	_c20090403
008			200904s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm8009537 _2doi
040			_aNLM _beng _cNLM
100	1		_aDyck, Brian
245	0	0	_aCharacterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain. _h[electronic resource]
260			_bJournal of medicinal chemistry _cNov 2008
300			_a7265-72 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAdministration, Oral
650	0	4	_aAnimals
650	0	4	_aBiological Availability
650	0	4	_aCaco-2 Cells
650	0	4	_aCrystallography, X-Ray
650	0	4	_aCyclopropanes _xchemistry
650	0	4	_aDisease Models, Animal
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Design
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aMicrosomes, Liver _xchemistry
650	0	4	_aMilnacipran
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Structure
650	0	4	_aMolecular Weight
650	0	4	_aNeuralgia _xdrug therapy
650	0	4	_aNorepinephrine Plasma Membrane Transport Proteins _xantagonists & inhibitors
650	0	4	_aPain Measurement _xdrug effects
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aSerotonin Plasma Membrane Transport Proteins _xmetabolism
650	0	4	_aSelective Serotonin Reuptake Inhibitors _xchemistry
650	0	4	_aSpinal Nerves _xpathology
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
700	1		_aTamiya, Junko
700	1		_aJovic, Florence
700	1		_aPick, Rebecca R
700	1		_aBradbury, Margaret J
700	1		_aO'Brien, Julie
700	1		_aWen, Jenny
700	1		_aJohns, Michael
700	1		_aMadan, Ajay
700	1		_aFleck, Beth A
700	1		_aFoster, Alan C
700	1		_aLi, Binfeng
700	1		_aZhang, Mingzhu
700	1		_aTran, Joe A
700	1		_aVickers, Troy
700	1		_aGrey, Jonathan
700	1		_aSaunders, John
700	1		_aChen, Chen
773	0		_tJournal of medicinal chemistry _gvol. 51 _gno. 22 _gp. 7265-72
856	4	0	_uhttps://doi.org/10.1021/jm8009537 _zAvailable from publisher's website
999			_c18416510 _d18416510