000			02235 a2200625 4500
005			20250515135316.0
264		0	_c20090424
008			200904s 0 0 eng d
022			_a1464-3405
024	7		_a10.1016/j.bmcl.2008.08.094 _2doi
040			_aNLM _beng _cNLM
100	1		_aDragovich, Peter S
245	0	0	_aNovel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cOct 2008
300			_a5635-9 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAntiviral Agents _xchemical synthesis
650	0	4	_aCaco-2 Cells
650	0	4	_aChemistry, Pharmaceutical _xmethods
650	0	4	_aCrystallography, X-Ray _xmethods
650	0	4	_aCyclic S-Oxides _xchemical synthesis
650	0	4	_aDNA-Directed RNA Polymerases _xchemistry
650	0	4	_aDrug Design
650	0	4	_aGenotype
650	0	4	_aHumans
650	0	4	_aInhibitory Concentration 50
650	0	4	_aMicrosomes _xmetabolism
650	0	4	_aModels, Chemical
650	0	4	_aMolecular Conformation
650	0	4	_aPyridazines _xchemical synthesis
650	0	4	_aStructure-Activity Relationship
650	0	4	_aThiadiazines _xchemical synthesis
650	0	4	_aViral Nonstructural Proteins _xantagonists & inhibitors
700	1		_aBlazel, Julie K
700	1		_aEllis, David A
700	1		_aHan, Qing
700	1		_aKamran, Ruhi
700	1		_aKissinger, Charles R
700	1		_aLeBrun, Laurie A
700	1		_aLi, Lian-Sheng
700	1		_aMurphy, Douglas E
700	1		_aNoble, Michael
700	1		_aPatel, Rupal A
700	1		_aRuebsam, Frank
700	1		_aSergeeva, Maria V
700	1		_aShah, Amit M
700	1		_aShowalter, Richard E
700	1		_aTran, Chinh V
700	1		_aTsan, Mei
700	1		_aWebber, Stephen E
700	1		_aKirkovsky, Leo
700	1		_aZhou, Yuefen
773	0		_tBioorganic & medicinal chemistry letters _gvol. 18 _gno. 20 _gp. 5635-9
856	4	0	_uhttps://doi.org/10.1016/j.bmcl.2008.08.094 _zAvailable from publisher's website
999			_c18264571 _d18264571