000			01940 a2200577 4500
005			20250515135230.0
264		0	_c20090424
008			200904s 0 0 eng d
022			_a1464-3405
024	7		_a10.1016/j.bmcl.2008.08.010 _2doi
040			_aNLM _beng _cNLM
100	1		_aTrani, Giancarlo
245	0	0	_aTricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cOct 2008
300			_a5698-700 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAntidepressive Agents, Tricyclic _xchemical synthesis
650	0	4	_aBlood-Brain Barrier _xdrug effects
650	0	4	_aBrain _xdrug effects
650	0	4	_aChemistry, Pharmaceutical _xmethods
650	0	4	_aCytochrome P-450 CYP3A
650	0	4	_aCytochrome P-450 Enzyme System _xchemistry
650	0	4	_aHumans
650	0	4	_aHydrogen Bonding
650	0	4	_aMicrosomes _xdrug effects
650	0	4	_aModels, Chemical
650	0	4	_aMolecular Conformation
650	0	4	_aProtein Isoforms
650	0	4	_aRats
650	0	4	_aReceptors, Serotonin _xchemistry
650	0	4	_aSerotonin Antagonists _xchemical synthesis
700	1		_aBaddeley, Stuart M
700	1		_aBriggs, Michael A
700	1		_aChuang, Tsu T
700	1		_aDeeks, Nigel J
700	1		_aJohnson, Christopher N
700	1		_aKhazragi, Abir A
700	1		_aMead, Tania L
700	1		_aMedhurst, Andrew D
700	1		_aMilner, Peter H
700	1		_aQuinn, Leann P
700	1		_aRay, Alison M
700	1		_aRivers, Dean A
700	1		_aStean, Tania O
700	1		_aStemp, Geoffrey
700	1		_aTrail, Brenda K
700	1		_aWitty, David R
773	0		_tBioorganic & medicinal chemistry letters _gvol. 18 _gno. 20 _gp. 5698-700
856	4	0	_uhttps://doi.org/10.1016/j.bmcl.2008.08.010 _zAvailable from publisher's website
999			_c18262216 _d18262216