000 | 01841 a2200493 4500 | ||
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005 | 20250515135132.0 | ||
264 | 0 | _c20081030 | |
008 | 200810s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2008.08.079 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aTong, Yunsong | |
245 | 0 | 0 |
_aIsoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _cOct 2008 |
||
300 |
_a5206-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aCombinatorial Chemistry Techniques |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aIsoxazoles _xchemical synthesis |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xantagonists & inhibitors |
650 | 0 | 4 |
_aProto-Oncogene Proteins _xantagonists & inhibitors |
650 | 0 | 4 |
_aProto-Oncogene Proteins c-pim-1 _xantagonists & inhibitors |
650 | 0 | 4 |
_aQuinolines _xchemical synthesis |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aStewart, Kent D | |
700 | 1 | _aThomas, Sheela | |
700 | 1 | _aPrzytulinska, Magdalena | |
700 | 1 | _aJohnson, Eric F | |
700 | 1 | _aKlinghofer, Vered | |
700 | 1 | _aLeverson, Joel | |
700 | 1 | _aMcCall, Owen | |
700 | 1 | _aSoni, Niru B | |
700 | 1 | _aLuo, Yan | |
700 | 1 | _aLin, Nan-horng | |
700 | 1 | _aSowin, Thomas J | |
700 | 1 | _aGiranda, Vincent L | |
700 | 1 | _aPenning, Thomas D | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 18 _gno. 19 _gp. 5206-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2008.08.079 _zAvailable from publisher's website |
999 |
_c18259252 _d18259252 |