000 01841 a2200493 4500
005 20250515135132.0
264 0 _c20081030
008 200810s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2008.08.079
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTong, Yunsong
245 0 0 _aIsoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cOct 2008
300 _a5206-8 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aCombinatorial Chemistry Techniques
650 0 4 _aCrystallography, X-Ray
650 0 4 _aHumans
650 0 4 _aIsoxazoles
_xchemical synthesis
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Structure
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-pim-1
_xantagonists & inhibitors
650 0 4 _aQuinolines
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
700 1 _aStewart, Kent D
700 1 _aThomas, Sheela
700 1 _aPrzytulinska, Magdalena
700 1 _aJohnson, Eric F
700 1 _aKlinghofer, Vered
700 1 _aLeverson, Joel
700 1 _aMcCall, Owen
700 1 _aSoni, Niru B
700 1 _aLuo, Yan
700 1 _aLin, Nan-horng
700 1 _aSowin, Thomas J
700 1 _aGiranda, Vincent L
700 1 _aPenning, Thomas D
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 18
_gno. 19
_gp. 5206-8
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2008.08.079
_zAvailable from publisher's website
999 _c18259252
_d18259252