000 02026 a2200601 4500
005 20250515134549.0
264 0 _c20080909
008 200809s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.1159974
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPrabhakar, Shyam
245 0 0 _aHuman-specific gain of function in a developmental enhancer.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_cSep 2008
300 _a1346-50 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aBase Sequence
650 0 4 _aBinding Sites
650 0 4 _aBody Patterning
_xgenetics
650 0 4 _aConserved Sequence
650 0 4 _aEmbryonic Development
650 0 4 _aEnhancer Elements, Genetic
650 0 4 _aEvolution, Molecular
650 0 4 _aExtremities
_xembryology
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Expression Regulation, Developmental
650 0 4 _aHumans
650 0 4 _aLimb Buds
_xembryology
650 0 4 _aMacaca mulatta
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutation
650 0 4 _aPAX9 Transcription Factor
_xmetabolism
650 0 4 _aPan troglodytes
_xgenetics
650 0 4 _aSelection, Genetic
650 0 4 _aTranscription Factors
_xmetabolism
700 1 _aVisel, Axel
700 1 _aAkiyama, Jennifer A
700 1 _aShoukry, Malak
700 1 _aLewis, Keith D
700 1 _aHolt, Amy
700 1 _aPlajzer-Frick, Ingrid
700 1 _aMorrison, Harris
700 1 _aFitzpatrick, David R
700 1 _aAfzal, Veena
700 1 _aPennacchio, Len A
700 1 _aRubin, Edward M
700 1 _aNoonan, James P
773 0 _tScience (New York, N.Y.)
_gvol. 321
_gno. 5894
_gp. 1346-50
856 4 0 _uhttps://doi.org/10.1126/science.1159974
_zAvailable from publisher's website
999 _c18242218
_d18242218