000			02055 a2200649 4500
005			20250515134525.0
264		0	_c20081030
008			200810s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm800525p _2doi
040			_aNLM _beng _cNLM
100	1		_aTian, Xinrong
245	0	0	_aDiscovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents. _h[electronic resource]
260			_bJournal of medicinal chemistry _cOct 2008
300			_a6055-66 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAdministration, Oral
650	0	4	_aAnimals
650	0	4	_aAnti-Obesity Agents _xchemistry
650	0	4	_aBiological Availability
650	0	4	_aDiet
650	0	4	_aDisease Models, Animal
650	0	4	_aDogs
650	0	4	_aDrug Design
650	0	4	_aDrug Evaluation, Preclinical
650	0	4	_aEating _xdrug effects
650	0	4	_aMale
650	0	4	_aMolecular Conformation
650	0	4	_aObesity _xdrug therapy
650	0	4	_aPiperazines _xchemistry
650	0	4	_aRats
650	0	4	_aReceptor, Melanocortin, Type 4 _xagonists
650	0	4	_aStereoisomerism
700	1		_aSwitzer, Adrian G
700	1		_aDerose, Steve A
700	1		_aMishra, Rajesh K
700	1		_aSolinsky, Mark G
700	1		_aMumin, Rashid N
700	1		_aEbetino, Frank H
700	1		_aJayasinghe, Lalith R
700	1		_aWebster, Mark E
700	1		_aColson, Anny-Odile
700	1		_aCrossdoersen, Doreen
700	1		_aPinney, Beth B
700	1		_aFarmer, Julie A
700	1		_aDowty, Martin E
700	1		_aObringer, Cindy M
700	1		_aCruze, Charles A
700	1		_aBurklow, Melissa L
700	1		_aSuchanek, Paula M
700	1		_aDong, Lily
700	1		_aDirr, Mary Kay
700	1		_aSheldon, Russell J
700	1		_aWos, John A
773	0		_tJournal of medicinal chemistry _gvol. 51 _gno. 19 _gp. 6055-66
856	4	0	_uhttps://doi.org/10.1021/jm800525p _zAvailable from publisher's website
999			_c18241068 _d18241068