000 | 01752 a2200469 4500 | ||
---|---|---|---|
005 | 20250515134412.0 | ||
264 | 0 | _c20080930 | |
008 | 200809s 0 0 eng d | ||
022 | _a1091-6490 | ||
024 | 7 |
_a10.1073/pnas.0800041105 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aFujishita, Teruaki | |
245 | 0 | 0 |
_aInhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. _h[electronic resource] |
260 |
_bProceedings of the National Academy of Sciences of the United States of America _cSep 2008 |
||
300 |
_a13544-9 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAdenoma _xblood supply |
650 | 0 | 4 |
_aAdenomatous Polyposis Coli Protein _xgenetics |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 | _aEverolimus |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 |
_aIntestinal Polyps _xmetabolism |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMechanistic Target of Rapamycin Complex 1 |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMice, Transgenic |
650 | 0 | 4 | _aMultiprotein Complexes |
650 | 0 | 4 | _aProteins |
650 | 0 | 4 |
_aSignal Transduction _xdrug effects |
650 | 0 | 4 |
_aSirolimus _xanalogs & derivatives |
650 | 0 | 4 | _aSurvival Rate |
650 | 0 | 4 | _aTOR Serine-Threonine Kinases |
650 | 0 | 4 |
_aTranscription Factors _xmetabolism |
650 | 0 | 4 |
_aWnt Proteins _xmetabolism |
700 | 1 | _aAoki, Koji | |
700 | 1 | _aLane, Heidi A | |
700 | 1 | _aAoki, Masahiro | |
700 | 1 | _aTaketo, Makoto M | |
773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 105 _gno. 36 _gp. 13544-9 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.0800041105 _zAvailable from publisher's website |
999 |
_c18238772 _d18238772 |