000 01430 a2200409 4500
005 20250515132650.0
264 0 _c20081024
008 200810s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm800321h
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRichardson, Robyn D
245 0 0 _aSynthesis of novel beta-lactone inhibitors of fatty acid synthase.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cSep 2008
300 _a5285-96 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aFatty Acid Synthases
_xantagonists & inhibitors
650 0 4 _aFibroblasts
650 0 4 _aHumans
650 0 4 _aLactones
_xchemical synthesis
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aOrlistat
650 0 4 _aSolubility
650 0 4 _aStructure-Activity Relationship
700 1 _aMa, Gil
700 1 _aOyola, Yatsandra
700 1 _aZancanella, Manuel
700 1 _aKnowles, Lynn M
700 1 _aCieplak, Piotr
700 1 _aRomo, Daniel
700 1 _aSmith, Jeffrey W
773 0 _tJournal of medicinal chemistry
_gvol. 51
_gno. 17
_gp. 5285-96
856 4 0 _uhttps://doi.org/10.1021/jm800321h
_zAvailable from publisher's website
999 _c18182797
_d18182797