000 02093 a2200589 4500
005 20250515130204.0
264 0 _c20080908
008 200809s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm800340w
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNawrozkij, Maxim B
245 0 0 _a5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cAug 2008
300 _a4641-52 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlkylation
650 0 4 _aAnti-HIV Agents
_xchemical synthesis
650 0 4 _aBenzene
_xchemistry
650 0 4 _aChemical Phenomena
650 0 4 _aChemistry, Physical
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aHIV-1
_xdrug effects
650 0 4 _aHydrogen
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aMutation
_xgenetics
650 0 4 _aOxygen
_xchemistry
650 0 4 _aProtein Binding
650 0 4 _aPyrimidinones
_xchemical synthesis
650 0 4 _aRNA-Directed DNA Polymerase
_xgenetics
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSulfur Compounds
_xchemical synthesis
700 1 _aRotili, Dante
700 1 _aTarantino, Domenico
700 1 _aBotta, Giorgia
700 1 _aEremiychuk, Alexandre S
700 1 _aMusmuca, Ira
700 1 _aRagno, Rino
700 1 _aSamuele, Alberta
700 1 _aZanoli, Samantha
700 1 _aArmand-Ugón, Mercedes
700 1 _aClotet-Codina, Imma
700 1 _aNovakov, Ivan A
700 1 _aOrlinson, Boris S
700 1 _aMaga, Giovanni
700 1 _aEsté, José A
700 1 _aArtico, Marino
700 1 _aMai, Antonello
773 0 _tJournal of medicinal chemistry
_gvol. 51
_gno. 15
_gp. 4641-52
856 4 0 _uhttps://doi.org/10.1021/jm800340w
_zAvailable from publisher's website
999 _c18111538
_d18111538