000 02080 a2200529 4500
005 20250515121916.0
264 0 _c20080626
008 200806s 0 0 eng d
022 _a1529-2401
024 7 _a10.1523/JNEUROSCI.0955-08.2008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMeikle, Lynsey
245 0 0 _aResponse of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
_h[electronic resource]
260 _bThe Journal of neuroscience : the official journal of the Society for Neuroscience
_cMay 2008
300 _a5422-32 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAge Factors
650 0 4 _aAnimals
650 0 4 _aAnimals, Newborn
650 0 4 _aBrain
_xdrug effects
650 0 4 _aCell Size
_xdrug effects
650 0 4 _aDendrites
_xdrug effects
650 0 4 _aDisease Models, Animal
650 0 4 _aEverolimus
650 0 4 _aImmunosuppressive Agents
_xtherapeutic use
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Transgenic
650 0 4 _aMutation
_xgenetics
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aOncogene Protein v-akt
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSirolimus
_xanalogs & derivatives
650 0 4 _aTime Factors
650 0 4 _aTranscription Factors
_xmetabolism
650 0 4 _aTuberous Sclerosis
_xdrug therapy
650 0 4 _aTuberous Sclerosis Complex 1 Protein
650 0 4 _aTumor Suppressor Proteins
_xgenetics
700 1 _aPollizzi, Kristen
700 1 _aEgnor, Anna
700 1 _aKramvis, Ioannis
700 1 _aLane, Heidi
700 1 _aSahin, Mustafa
700 1 _aKwiatkowski, David J
773 0 _tThe Journal of neuroscience : the official journal of the Society for Neuroscience
_gvol. 28
_gno. 21
_gp. 5422-32
856 4 0 _uhttps://doi.org/10.1523/JNEUROSCI.0955-08.2008
_zAvailable from publisher's website
999 _c17989815
_d17989815