000 01607 a2200433 4500
005 20250515115855.0
264 0 _c20080715
008 200807s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2008.04.002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWolin, Ronald L
245 0 0 _aDual binding site inhibitors of B-RAF kinase.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cMay 2008
300 _a2825-9 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdenosine Triphosphate
_xmetabolism
650 0 4 _aAllosteric Site
650 0 4 _aComputer-Aided Design
650 0 4 _aCrystallography, X-Ray
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xantagonists & inhibitors
650 0 4 _aHydrocarbons, Aromatic
_xchemical synthesis
650 0 4 _aImidazoles
_xchemical synthesis
650 0 4 _aInhibitory Concentration 50
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xchemical synthesis
650 0 4 _aProto-Oncogene Proteins B-raf
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
700 1 _aBembenek, Scott D
700 1 _aWei, Jianmei
700 1 _aCrawford, Shelby
700 1 _aLundeen, Katherine
700 1 _aBrunmark, Anders
700 1 _aKarlsson, Lars
700 1 _aEdwards, James P
700 1 _aBlevitt, Jonathan M
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 18
_gno. 9
_gp. 2825-9
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2008.04.002
_zAvailable from publisher's website
999 _c17931158
_d17931158