000 02071 a2200613 4500
005 20250515111102.0
264 0 _c20080605
008 200806s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm070579c
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChen, Yuhpyng L
245 0 0 _a2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMar 2008
300 _a1385-92 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAction Potentials
_xdrug effects
650 0 4 _aAdministration, Oral
650 0 4 _aAdrenocorticotropic Hormone
_xblood
650 0 4 _aAminopyridines
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aAntidepressive Agents
_xchemical synthesis
650 0 4 _aCerebral Cortex
_xmetabolism
650 0 4 _aCorticotropin-Releasing Hormone
_xpharmacology
650 0 4 _aDogs
650 0 4 _aFasting
650 0 4 _aHumans
650 0 4 _aInjections, Intravenous
650 0 4 _aLocus Coeruleus
_xphysiology
650 0 4 _aMale
650 0 4 _aPituitary Gland
_xmetabolism
650 0 4 _aPostprandial Period
650 0 4 _aRadioligand Assay
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReceptors, Corticotropin-Releasing Hormone
_xantagonists & inhibitors
650 0 4 _aReflex, Startle
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aCRF Receptor, Type 1
700 1 _aObach, R Scott
700 1 _aBraselton, John
700 1 _aCorman, Michael L
700 1 _aForman, James
700 1 _aFreeman, Jody
700 1 _aGallaschun, Randall J
700 1 _aMansbach, Robert
700 1 _aSchmidt, Anne W
700 1 _aSprouse, Jeffrey S
700 1 _aTingley Iii, F David
700 1 _aWinston, Elizabeth
700 1 _aSchulz, David W
773 0 _tJournal of medicinal chemistry
_gvol. 51
_gno. 5
_gp. 1385-92
856 4 0 _uhttps://doi.org/10.1021/jm070579c
_zAvailable from publisher's website
999 _c17792997
_d17792997