000 01907 a2200481 4500
005 20250515110521.0
264 0 _c20080515
008 200805s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2008.01.047
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aReddy, M V Ramana
245 0 0 _aDesign, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cApr 2008
300 _a3907-16 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aBinding Sites
650 0 4 _aBlood Platelets
_xdrug effects
650 0 4 _aCyclooxygenase 2
_xchemistry
650 0 4 _aCyclooxygenase 2 Inhibitors
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aFluorine Compounds
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aHydrogen Bonding
650 0 4 _aIndoles
_xchemistry
650 0 4 _aLipoxygenase Inhibitors
_xchemical synthesis
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMethylation
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aPyrazoles
_xchemical synthesis
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSulfur Compounds
_xchemical synthesis
700 1 _aBilla, Vinay K
700 1 _aPallela, Venkat R
700 1 _aMallireddigari, Muralidhar R
700 1 _aBoominathan, Rengasamy
700 1 _aGabriel, Jerome L
700 1 _aReddy, E Premkumar
773 0 _tBioorganic & medicinal chemistry
_gvol. 16
_gno. 7
_gp. 3907-16
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2008.01.047
_zAvailable from publisher's website
999 _c17777270
_d17777270