| 000 | 01918 a2200529 4500 | ||
|---|---|---|---|
| 005 | 20250515105321.0 | ||
| 264 | 0 | _c20080512 | |
| 008 | 200805s 0 0 eng d | ||
| 022 | _a1464-3405 | ||
| 024 | 7 |
_a10.1016/j.bmcl.2008.01.030 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aOtt, Gregory R | |
| 245 | 0 | 0 |
_aAlpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE). _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _cFeb 2008 |
||
| 300 |
_a1288-92 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aADAM Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 | _aADAM17 Protein |
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 |
_aAlkanes _xchemical synthesis |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aBiological Availability |
| 650 | 0 | 4 | _aCaco-2 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHydroxamic Acids _xchemical synthesis |
| 650 | 0 | 4 | _aMatrix Metalloproteinase Inhibitors |
| 650 | 0 | 4 |
_aMatrix Metalloproteinases _xmetabolism |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aProtease Inhibitors _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 |
_aSpiro Compounds _xchemical synthesis |
| 700 | 1 | _aAsakawa, Naoyuki | |
| 700 | 1 | _aLiu, Rui-Qin | |
| 700 | 1 | _aCovington, Maryanne B | |
| 700 | 1 | _aQian, Mingxin | |
| 700 | 1 | _aVaddi, Krishna | |
| 700 | 1 | _aNewton, Robert C | |
| 700 | 1 | _aTrzaskos, James M | |
| 700 | 1 | _aChrist, David D | |
| 700 | 1 | _aGalya, Laurine | |
| 700 | 1 | _aScholz, Thomas | |
| 700 | 1 | _aMarshall, Will | |
| 700 | 1 | _aDuan, James J-W | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 18 _gno. 4 _gp. 1288-92 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2008.01.030 _zAvailable from publisher's website |
| 999 |
_c17741176 _d17741176 |
||