000 | 01907 a2200541 4500 | ||
---|---|---|---|
005 | 20250515103535.0 | ||
264 | 0 | _c20080324 | |
008 | 200803s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2007.12.028 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aGhosh, Arun K | |
245 | 0 | 0 |
_aPotent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _cFeb 2008 |
||
300 |
_a1031-6 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural | ||
650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
650 | 0 | 4 |
_aAmyloid Precursor Protein Secretases _xantagonists & inhibitors |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAspartic Acid _xanalogs & derivatives |
650 | 0 | 4 |
_aAspartic Acid Endopeptidases _xantagonists & inhibitors |
650 | 0 | 4 | _aCricetinae |
650 | 0 | 4 | _aCricetulus |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 |
_aDipeptides _xchemical synthesis |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMice, Transgenic |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aSulfonamides _xchemical synthesis |
700 | 1 | _aKumaragurubaran, Nagaswamy | |
700 | 1 | _aHong, Lin | |
700 | 1 | _aKulkarni, Sarang | |
700 | 1 | _aXu, Xiaoming | |
700 | 1 | _aMiller, Heather B | |
700 | 1 | _aReddy, Dandepally Srinivasa | |
700 | 1 | _aWeerasena, Vajira | |
700 | 1 | _aTurner, Robert | |
700 | 1 | _aChang, Wanpin | |
700 | 1 | _aKoelsch, Gerald | |
700 | 1 | _aTang, Jordan | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 18 _gno. 3 _gp. 1031-6 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2007.12.028 _zAvailable from publisher's website |
999 |
_c17690147 _d17690147 |