000 01907 a2200541 4500
005 20250515103535.0
264 0 _c20080324
008 200803s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2007.12.028
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGhosh, Arun K
245 0 0 _aPotent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cFeb 2008
300 _a1031-6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAspartic Acid
_xanalogs & derivatives
650 0 4 _aAspartic Acid Endopeptidases
_xantagonists & inhibitors
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDipeptides
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSulfonamides
_xchemical synthesis
700 1 _aKumaragurubaran, Nagaswamy
700 1 _aHong, Lin
700 1 _aKulkarni, Sarang
700 1 _aXu, Xiaoming
700 1 _aMiller, Heather B
700 1 _aReddy, Dandepally Srinivasa
700 1 _aWeerasena, Vajira
700 1 _aTurner, Robert
700 1 _aChang, Wanpin
700 1 _aKoelsch, Gerald
700 1 _aTang, Jordan
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 18
_gno. 3
_gp. 1031-6
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2007.12.028
_zAvailable from publisher's website
999 _c17690147
_d17690147