000			02184 a2200661 4500
005			20250515100858.0
264		0	_c20080417
008			200804s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm0709034 _2doi
040			_aNLM _beng _cNLM
100	1		_aSmith, Brian M
245	0	0	_aDiscovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJan 2008
300			_a305-13 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAnti-Obesity Agents _xchemical synthesis
650	0	4	_aBenzazepines _xchemical synthesis
650	0	4	_aCell Line
650	0	4	_aEating _xdrug effects
650	0	4	_aHumans
650	0	4	_aInositol 1,4,5-Trisphosphate _xmetabolism
650	0	4	_aMale
650	0	4	_aObesity _xdrug therapy
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aSerotonin 5-HT2 Receptor Agonists
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
650	0	4	_aWeight Gain _xdrug effects
700	1		_aSmith, Jeffrey M
700	1		_aTsai, James H
700	1		_aSchultz, Jeffrey A
700	1		_aGilson, Charles A
700	1		_aEstrada, Scott A
700	1		_aChen, Rita R
700	1		_aPark, Douglas M
700	1		_aPrieto, Emily B
700	1		_aGallardo, Charlemagne S
700	1		_aSengupta, Dipanjan
700	1		_aDosa, Peter I
700	1		_aCovel, Jon A
700	1		_aRen, Albert
700	1		_aWebb, Robert R
700	1		_aBeeley, Nigel R A
700	1		_aMartin, Michael
700	1		_aMorgan, Michael
700	1		_aEspitia, Stephen
700	1		_aSaldana, Hazel R
700	1		_aBjenning, Christina
700	1		_aWhelan, Kevin T
700	1		_aGrottick, Andrew J
700	1		_aMenzaghi, Frederique
700	1		_aThomsen, William J
773	0		_tJournal of medicinal chemistry _gvol. 51 _gno. 2 _gp. 305-13
856	4	0	_uhttps://doi.org/10.1021/jm0709034 _zAvailable from publisher's website
999			_c17607950 _d17607950