000 01537 a2200385 4500
005 20250515100858.0
264 0 _c20080417
008 200804s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm0708735
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJohnson, Steven M
245 0 0 _aBiochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 2008
300 _a260-70 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmyloid
_xantagonists & inhibitors
650 0 4 _aBenzoxazoles
_xchemical synthesis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCyclooxygenase 1
_xchemistry
650 0 4 _aCyclooxygenase Inhibitors
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aLiver
_xmetabolism
650 0 4 _aModels, Molecular
650 0 4 _aPrealbumin
_xantagonists & inhibitors
650 0 4 _aProtein Conformation
650 0 4 _aReceptors, Thyroid Hormone
_xmetabolism
650 0 4 _aStructure-Activity Relationship
700 1 _aConnelly, Stephen
700 1 _aWilson, Ian A
700 1 _aKelly, Jeffery W
773 0 _tJournal of medicinal chemistry
_gvol. 51
_gno. 2
_gp. 260-70
856 4 0 _uhttps://doi.org/10.1021/jm0708735
_zAvailable from publisher's website
999 _c17607949
_d17607949