000 01870 a2200565 4500
005 20250515100614.0
264 0 _c20080115
008 200801s 0 0 eng d
022 _a1091-6490
024 7 _a10.1073/pnas.0707731105
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDeLuca, G C
245 0 0 _aAn extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cDec 2007
300 _a20896-901 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAlleles
650 0 4 _aDisease Progression
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation
650 0 4 _aGene Frequency
650 0 4 _aGenetic Predisposition to Disease
650 0 4 _aHLA-DR Antigens
_xgenetics
650 0 4 _aHLA-DRB1 Chains
650 0 4 _aHumans
650 0 4 _aItaly
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aModels, Genetic
650 0 4 _aMultiple Sclerosis
_xdiagnosis
650 0 4 _aPhenotype
650 0 4 _aPolymorphism, Single Nucleotide
650 0 4 _aTreatment Outcome
700 1 _aRamagopalan, S V
700 1 _aHerrera, B M
700 1 _aDyment, D A
700 1 _aLincoln, M R
700 1 _aMontpetit, A
700 1 _aPugliatti, M
700 1 _aBarnardo, M C N
700 1 _aRisch, N J
700 1 _aSadovnick, A D
700 1 _aChao, M
700 1 _aSotgiu, S
700 1 _aHudson, T J
700 1 _aEbers, G C
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 104
_gno. 52
_gp. 20896-901
856 4 0 _uhttps://doi.org/10.1073/pnas.0707731105
_zAvailable from publisher's website
999 _c17599864
_d17599864