000 | 02432 a2200805 4500 | ||
---|---|---|---|
005 | 20250515095235.0 | ||
264 | 0 | _c20080107 | |
008 | 200801s 0 0 eng d | ||
022 | _a1476-4687 | ||
024 | 7 |
_a10.1038/nature06261 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aMilne, Jill C | |
245 | 0 | 0 |
_aSmall molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. _h[electronic resource] |
260 |
_bNature _cNov 2007 |
||
300 |
_a712-6 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAcetylation |
650 | 0 | 4 | _aAllosteric Site |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aBlood Glucose _xmetabolism |
650 | 0 | 4 | _aCaloric Restriction |
650 | 0 | 4 | _aCatalytic Domain |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 |
_aDiabetes Mellitus, Type 2 _xdrug therapy |
650 | 0 | 4 |
_aDietary Fats _xadministration & dosage |
650 | 0 | 4 | _aDisease Models, Animal |
650 | 0 | 4 | _aDrosophila melanogaster |
650 | 0 | 4 |
_aHeterocyclic Compounds, 4 or More Rings _xpharmacology |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aInsulin _xmetabolism |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aMitochondria _xdrug effects |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aRats, Sprague-Dawley |
650 | 0 | 4 | _aRats, Zucker |
650 | 0 | 4 | _aResveratrol |
650 | 0 | 4 | _aSirtuin 1 |
650 | 0 | 4 |
_aSirtuins _xagonists |
650 | 0 | 4 |
_aStilbenes _xchemistry |
700 | 1 | _aLambert, Philip D | |
700 | 1 | _aSchenk, Simon | |
700 | 1 | _aCarney, David P | |
700 | 1 | _aSmith, Jesse J | |
700 | 1 | _aGagne, David J | |
700 | 1 | _aJin, Lei | |
700 | 1 | _aBoss, Olivier | |
700 | 1 | _aPerni, Robert B | |
700 | 1 | _aVu, Chi B | |
700 | 1 | _aBemis, Jean E | |
700 | 1 | _aXie, Roger | |
700 | 1 | _aDisch, Jeremy S | |
700 | 1 | _aNg, Pui Yee | |
700 | 1 | _aNunes, Joseph J | |
700 | 1 | _aLynch, Amy V | |
700 | 1 | _aYang, Hongying | |
700 | 1 | _aGalonek, Heidi | |
700 | 1 | _aIsraelian, Kristine | |
700 | 1 | _aChoy, Wendy | |
700 | 1 | _aIffland, Andre | |
700 | 1 | _aLavu, Siva | |
700 | 1 | _aMedvedik, Oliver | |
700 | 1 | _aSinclair, David A | |
700 | 1 | _aOlefsky, Jerrold M | |
700 | 1 | _aJirousek, Michael R | |
700 | 1 | _aElliott, Peter J | |
700 | 1 | _aWestphal, Christoph H | |
773 | 0 |
_tNature _gvol. 450 _gno. 7170 _gp. 712-6 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/nature06261 _zAvailable from publisher's website |
999 |
_c17561241 _d17561241 |