000 01432 a2200373 4500
005 20250515094446.0
264 0 _c20080603
008 200806s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2007.11.004
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFortin, Sébastien
245 0 0 _aA comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cFeb 2008
300 _a1914-26 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntimitotic Agents
_xchemistry
650 0 4 _aBinding Sites
650 0 4 _aColchicine
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aModels, Molecular
650 0 4 _aQuantitative Structure-Activity Relationship
650 0 4 _aTubulin
_xmetabolism
650 0 4 _aTubulin Modulators
_xchemistry
650 0 4 _aUrea
_xanalogs & derivatives
700 1 _aLabrie, Philippe
700 1 _aMoreau, Emmanuel
700 1 _aWei, Lianhu
700 1 _aKotra, Lakshmi P
700 1 _aC-Gaudreault, René
773 0 _tBioorganic & medicinal chemistry
_gvol. 16
_gno. 4
_gp. 1914-26
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2007.11.004
_zAvailable from publisher's website
999 _c17539829
_d17539829